ANTIACETYLCHOLINE ACTION OF IMIPRAMINE
نویسندگان
چکیده
منابع مشابه
Antiacetycholine action of imipramine.
Imipramine, a potent antidepressive drug has been shown to antagonize the actions of a number of autopharmacological substances like histamine, 5-hydroxytryptamine, bradykinin, catecholamines and acetylcholine (1). Sigg and his coworkers (2, 3) observed a dual effect of imipramine on the various manifestations of the autonomic nervous system; a blocking action at higher dosage and a stimulant e...
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Dikstein and Sulman (1) reported that the treatment of the rectus abdominis muscle of Bufo viridis toad with 3.4 M (25%) acetone for 2 minutes eliminated the response of the muscle to acetylcholine (ACh), but 5 to 20 ag/ml of phospholipids such as phospha tidylserine could restore the response of the treated muscle to ACh. They also observed similar effects of phospholipids on the rabbit uterus...
متن کاملEffects of calcium channel blockers on antidepressant action of Alprazolam and Imipramine
Alprazolam is effective as an anxiolytic and in the adjunct treatment of depression. In this study, the effects of calcium channel antagonists on the antidepressant action of alprazolam and imipramine were investigated. A forced swimming maze was used to study behavioral despair in albino mice. Mice were divided into nine groups (n = 7 per group). One group received a single dose of 1% Tween 80...
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OBJECTIVE To evaluate the behavioral effect of pyridoxine on the antidepressant action of imipramine. METHODS Male Wistar albino mice of weights 25-35gms were used. Two experiments were carried out; the first on the acute effect of pyridoxine on the duration of immobility, and the second on the sub-chronic effects of pyridoxine alone and in combination with imipramine. In the first experiment...
متن کاملRapidly progressive polymyositis with elevated antiacetylcholine receptor antibody activity.
We report a 51-year-old woman with polymyositis accompanied by a high titer of antiacetylcholine receptor antibody. The patient presented with weakness of grip strength followed by rapidly progressive dyspnea, which required mechanical ventilation. She was treated with a glucocorticoid and came off the respirator one week later. Antiacetylcholine receptor antibody activity was elevated in the a...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1968
ISSN: 0021-5198
DOI: 10.1254/jjp.18.509